Abstract of research

Comparative therapeutic effect of three types of antibiotics on pneumonia associated with klebsiella pneumoniae in boer goats.

Ghanem, M.M.1, Yousif, H.M.2, Abd El-Ghany, A.H.1, Abd El-Raof, Y.M.1, El-Attar, H.M.1

Abstract

Pneumonia in Boer goats is a multifactorial disease required a special care for economic, effictive and rapid treatment. Therefore, this study aimed to compare the therapeutic efficacy of three antibiotics (Tulathromycin, Florfenicol and Amoxicillin) in treatment of klebsiella pneumoniae in Boer goat. Forty five pneumonic Boer goats suffered from respiratory distress that were divided into three groups (each of 15) according to the type of the antibiotic used (Tulathromycin, Florfenicol and Amoxicillin). All Boer goats were examined before treatment (0 day) and on the 1st, 3rd, 5th and 7th days post treatment. The results revealed a clinical recovery of 80%, 73.3% and 60% of cases after first dose of tulathromycin, florfenicol and amoxicillin, respectively. The results of hematological, serum biochemicals and pulmonary function tests revealed improvement of most of parameters from the 3rd day of treatment by tulathromycin and florfenicol. However, treatment by amoxicillin restored the parameters from the 5th day and might be extended to the 7th day of treatment. Isolates were subcultured and confirmed as K. pneumoniae using standard microbiology techniques. The results were confirmed by the result of antibiotic sensitivity test against klebsiella which was highly sensitive to tulathromycin, sensitive to florfenicol and moderately sensitive to amoxicillin. We concluded that tulathromycin has a better efficacy than florfenicol and amoxicillin in treatment of Boer goats affected with k. pneumoniae.