Abstract of research

Clostridium perfringens in meat and chicken received to University student hostel

Ghanem, MM, Soha Elsadek, Abdel-Raof, YM, and El-Attar, HE.

Abstract

This study was conducted to evaluate the therapeutic efficacy of new herbal supplements in sheep after induction of lactic acidosis. To achieve this goal, five sheep were used in two experiments in a crossover design with an interval of three weeks. In addition, 10 apparently healthy sheep were used as control. In the first experiment, lactic acidosis was induced with sucrose (18 gm / kg b.wt) and treated with Rumitone powder. In the second experiment, sheep were treated with both Rumitone and Meboliv AFS. Within 24 hrs of induction, the affected sheep showed anorexia, weakness, depression, lowered head, semisolid feces, distended abdomen, dyspnea, incoordination and recumbency. The acidotic sheep showed significant (p< 0.05) increase in respiratory and pulse rates; and significant decrease in temperature and ruminal movement. There was a significant increase (p< 0.05) in Hb conc., PCV%, RBCs, WBCs, granulocyte% and lymphocyte%. Biochemically, there were significant decreases in serum Na, Cl, Ca, albumin and total protein; whereas significant increases in K and P, AST and ALT, urea and creatinine were observed. The clinical, hematological, biochemical and ruminal parameters were significantly changed toward the control values post-treatment with Rumitone alone and combination of Rumitone and Meboliv AFS. Therefore, these herbal compounds are recommended for treatment of ruminal acidosis in sheep.