Abstract of research

EFFECT OF SOME THERAPIES ON FUNCTIONAL REPRODUCTIVE EFFICIENCY IN A RABBIT MODEL

Waleed T. M. El Sayed, Alaa E. Abdel-Ghaffar, Abd Elsalam I. El Azab*

Abstract

The present study aimed at evaluating the efficacy of intervention with calcium, gonadotrophic releasing hormone (GnRH) or bromocriptine (BCr) on the reproductive performance and fertility traits of lactating does. For this purpose, NZW pluriparous does (n=120) were allocated into one of four treated groups: first three groups received 100 mg/head calcium citrate tablets orally, 0.8 μg of GnRH i.m or 2.5 mg of BCr orally. The remaining group was left as control. GnRH and BCr significantly (P<0.05) affected the ovarian biometry in opposite direction i.e. while the former increased the later decreased the ovarian biometry. Microscopically, treated group showed a mild (in GnRH), moderate (in BCr) and high (in calcium) rate of follicular growth. Luteinization of stromal cells was high in calcium and GnRH groups and moderate after BCr treatment. Calcium significantly (P<0.05) increased the intermediate cells at the 8th hour post treatment, while no considerable changes were recorded in other groups. GnRH and BCr substantially increased progesterone level when compared to control. The pregnancy rate was lower after calcium, GnRH and anti-prolactin treatments as compared with control. Litter number and size was higher in the calcium group. Litter number was low in GnRH and moderate in BCr.